190 - comedk january 2008 paper mcqs with answers part 35

176q: the supraoptic nucleus of the hypothalamus is believed to control secretion of which of the following hormones ?

a. antidiuretic hormone
b. oxytocin
c. growth hormone
d. adrenocorticotrophic hormone

answer a. antidiuretic hormone

177q: which among the following drugs is safest in a patient allergic to pencillin ?

a. cephalexin
b. imipenem
c. cefepime
d. aztreonam

answer d. aztreonam

178q: microalbuminuria is defined as protein levels of ?

a. 100-150 mg/l
b. 151-200 mg/l
c. 201-300 mg/l
d. 301-600 mg/l

answer b. 151-200 mg/l

179q: commonest tumor of the cervix is ?

a. squamous cell carcinoma
b. adenocarcinoma
c. sarcoma
d. adenoacanthoma

answer a. squamous cell carcinoma

180q: proximal convoluted tubule have which type of aquaporins ?

a. aquaporin 1
b. aquaporin 2
c. aquaporin 5
d. aquaporin 9

answer a. aquaporin

189 - comedk january 2008 paper mcqs with answers part 35

171q: which one given below is a DNA virus ?

a. polio virus
b. adeno virus
c. parvo virus
d. hepatitis-A virus

answer b and c . adeno and parvo virus

172q: which of the following drugs can help the ductus arteriosus to be patent prior ro surgery for pulmonary stenosis in a neonate ?

a. alprostadil
b. indomethacin
c. carboprost
d. misoprostol

answer a. alprostadil

173q: which of the following nerve fibers carry pain ?

a. A alpha
b. A beta
c. A gamma
d. A delta

answer d. A delta fibers

174q: alpha fetoprotein is genetically and structurally related to ?

a. albumin
b. transferrin
c. fibrinogen
d. growth hormone

answer a. albumin

175q: which muscle is an abductor of the vocal cords ?

a. transverse arytenoid
b. oblique arytenoid
c. lateral thyroarytenoid
d. posterior cricoarytenoid

answer d. posterior cricoarytenoid

188 - comedk january 2008 paper mcqs with answers part 34

166q: bilateral renal cell carcinoma is seen in ?

a. eagle barett’s syndrome
b. beckwith weideman syndrome
c. von hippel lindau disease
d. bilateral angiomyolipoma

answer c. von hippel lindau disease

167q: “ maldon teeth “ is due to ?

a. lead
b. fluoride
c. calcium
d. phosphorous

answer b. fluoride

168q: the most common form of diabetic neuropathy is ?

a. acute mononeuropathy
b. autonomic neuropathy
c. polyradiculopathy
d. distal symmetric polyneuropathy

answer d. distal symmetric polyneuropathy

169q: Bhopal gas tragedy is an example of ?

a. point source epidemic
b. continuous epidemic
c. propagated epidemic
d. slow epidemic

answer a. point source epidemic

170q: sex can be established by examining hair root cells for the presence of ?

a. Davidson body
b. Barr body
c. Golgi body
d. Medullary index

answer b. barr body

187 - comedk january 2008 paper mcqs with answers part 33

161q: the following are associated with fibular hemimelia except ?

a. short tibia
b. anterior bowing of the leg
c. equino-valgus deformity of the foot and ankle
d. presence of polydactyly

answer d. presence of polydactyly

162q: in an asthmatic patient which of the following pulmonary functions would show the greater improvement on inhaling a bronchodilator ?

a. tidal volume
b. FEV1
c. FEF 25%-75%
d. FVC

answer b. FEV1

163q: linear striations are typically seen in ?

a. vertebral myeloma
b. vertebral lymphangiomas
c. vertebral metastases
d. vertebral hemangiomas

answer d. vertebral hemangiomas

164q: bone infarcts are seen in ?

a. iron deficiency anemia
b. thalassemia
c. sickle cell anemia
d. hereditary spherocytosis

answer c. sickle cell anemia

165q: the most common organism isolated in emphysematous pyelonephritis is ?

a. E.Coli
b. Proteus
c. Pseudomonas
d. Klebsiella

answer a. E Coli

186 - comedk january 2008 paper mcqs with answers part 32

156q: Ghrelin is responsible for ?

a. stimulation of appetite
b. suppression of appetite
c. stimulation of sleep
d. suppression of sleep

answer a. stimulation of appetite

157q: prepyloric or channel ulcer in the stomach is termed as ?

a. type 1
b. type 2
c. type 3
d. type 4

answer c. type 3

158q: Delphic nodes are ?

a. pretracheal
b. paratracheal
c. supraclavicular
d. posterior triangle

answer a. pretracheal

159q: selenium sulfide is indicated for treating ?

a. tinea versicolor
b. tinea corporis
c. mixed mycotic infections
d. candidiasis only

answer a. tinea versicolor

160q: which of the immunoglobulins is associated with allergic disorders ?

a. Ig G
b. Ig M
c. Ig A
d. Ig E

answer d. Ig E

185 - comedk january 2008 paper mcqs with answers part 31

151q: all of the following are tumor necrosis factor blocking agents except ?

a. adalimumab
b. etanercept
c. infliximab
d. abciximab

answer d. abciximab

152q: which virus given below is not a teratogenic virus ?

a. rubella
b. cytomegalovirus
c. herpes simplex
d. measles

answer d. measles

153q: postmortem rigidity first starts in

a. eyelids
b. neck
c. upper limbs
d. lower limbs

answer a. eyelids

154q: The anopheles species most commonly found in coastal regions is

a. pheles philippinensis
b. anopheles stephensi
c. anopheles fluviatilis
d. anopheles minimus

answer b. anopheles stephensi

155q. Increased frequency of HLA-B 27 is seen in all of the following diseases except ?

a. ankylosing spondylitis
b. reiters syndrome
c. acute anterior uveitis
d. myasthenia gravis

answer d. myasthenia gravis

184 - comedk january 2008 paper mcqs with answers part 30

146q: agoraphobia is a disorder characterized by all of the following except ?

a. visual hallucinations
b. avoidance of situations in which it is difficult to obtain help
c. presence of panic symptoms
d. avoidance of being outside alone

answer a. visual hallucinations

147q: objective assessment of the refractive state of the eye is termed ?

a. retinoscopy
b. gonioscopy
c. opthalmoscopy
d. keratoscopy

answer a. retinoscopy

148q: the single most important sign in suspecting early volkmann’s contracture is ?

a. pallor of the fingers
b. pain
c. obliteration of the pulse
d. paralysis of the involved muscles

answer b. pain

149q: gartner’s duct is a remnant of ?

a. mullerian duct
b. wollfian duct
c. cloacal duct
d. epophoron

answer b. wollfian duct

150q: which immunoglobulin crosses placenta ?

a. Ig M
b. Ig A
c. Ig G
d. Ig D

answer c. Ig G

183 - comedk january 2008 paper mcqs with answers part 29

141q: the limit if loudness expressed as decibels that people can tolerate without substantial damage to their hearing is ?

a. 55
b. 65
c. 75
d. 85

answer d. 85

142q: the species origin of blood can be detected by ?

a. benzidine test
b. takayama test
c. spectroscopy
d. precipitin test

answer d. precipitin test

143q: sling psychrometer is used for measuring ?

a. air velocity
b. rainfall
c. median radiant temperature
d. relative humidity

answer d. relative humidity

144q: fetishism is a sexual perversion characterized by ?

a. sexual focus on children
b. sexual focus on genital rubbing
c. sexual pleasure from pain
d. sexual pleasure derived from non living objects

answer d. sexual pleasure derived from non living objects

145q: emporiatrics deals with the health of the ?

a. farmers
b. travelers
c. industrial workers
d. mine workers

answer b. travelers

182 - comedk january 2008 paper mcqs with answers part 28

136q: in case of a drug that follows first order elimination ?

a. the rate of elimination is constant
b. the elimination half life varies with dose
c. the clearance varies with dose
d. the rate of elimination varies directly with dose

answer d. the rate of elimination varies directly with dose

137q: a major lipid of mitochondrial membrane is ?

a. lecithin
b. inositol
c. plasmalogen
d. cardiolipin

answer d. cardiolipin

138q: which of the following tendons is lengthened in posteromedial soft tissue release for idiopathic congenital talipes equinovarus ?

a. tibialis anterior
b. tibialis posterior
c. extensor digitorum longus
d. flexor hallucis longus

answer b. tibialis posterior

139q: all of the following are used for first trimester MTP except ?

a. dilatation and evacuation
b. RU 486
c. Suction and evacuation
d. Ethacrydine extra amniotic

answer d. ethacrydine extra amniotic

140q: gustatory hallucinations are most commonly associated with ?

a. temporal lobe epilepsy
b. grand mal epilepsy
c. anxiety disorders
d. tobacco dependence

answer a. temporal lobe epilepsy

181 - comedk january 2008 paper mcqs with answers part 27

131q: pendred’s syndrome is due to a defect in ?

a. chromosome 7p
b. chromosome 7q
c. chromosome 8p
d. chromosome 8q

answer a. chromosome 7p

132q: fecal leucocytes are absent in all the following except ?

a. giardiasis
b. cryptosporidiasis
c. campylobacter infection
d. clostridium perfringes infection

answer c. campylobacter infection

133q: the recommended drug for the prophylaxis of influenza A and B is ?

a. acyclovir
b. ganciclovir
c. amantadine
d. foscarnet

answer c. amantadine

134q: spontaneous absorption of lenticular material is seen in ?

a. myotonic dystrophy
b. hallerman streiff syndrome
c. aniridia
d. persistent hyperplastic primary vitreous

answer b. hallermann sheriff syndrome

135q: an increase in protein without pleocytosis in CSF is seen in ?

a. froin’s syndrome
b. guillain barre syndrome
c. pyogenic meningitis
d. tuberculous meningitis

answer b. guillain barre syndrome

180 - comedk january 2008 paper mcqs with answers part 26

126q: the first line of treatment of open angle glaucoma is ?

a. timolol
b. pilocarpine
c. epinephrine
d. carbonic anhydrase inhibitor

answer a. timolol

127q: the following bacteria can invade intact corneal epithelium except ?

a. neisseria gonorrhea
b. haemophilus influenzae
c. staphylococcus aureus
d. listeria species

answer c. staphylococcus aureus

128q: duffy blood group antigen negativity confers protection against infection by ?

a. plasmodium falciparum
b. plasmodium ovale
c. plasmodium vivax
d. plasmodium malariae

answer c. plasmodium vivax

129q: in a 6 year old child with burns involving the whole of head and trunk , the estimated body surface area of burns is ?

a. 44 %
b. 52 %
c. 55 %
d. 58 %

answer b. 52 %

130q: most common medial meniscal tear is ?

a. longitudinal tear
b. oblique tear
c. radical tear
d. horizontal tear

answer a. longitudinal tear

179 - comedk january 2008 paper mcqs with answers part 25

121q: sclera is thinnest at ?

a. limbus
b. insertion of recti
c. posterior pole
d. equator

answer b. insertion of recti

122q: onion skin thickening of arteriolar wall is seen in ?

a. atherosclerosis
b. medial calcific sclerosis
c. hyaline arteriosclerosis
d. hyperplastic arteriosclerosis

answer d. hyperplastic arteriosclerosis

123q: the principal polypeptide that increases food intake are the following except ?

a. neuropeptides – Y
b. leptin
c. orexin – A
d. B-endorphin

answer b. leptin

124q: the cofactor required for the activity of sulfite oxidase is ?

a. copper
b. selenium
c. molybdenum
d. zinc

answer c. molybdenum

125q: c AMP action mediates all except ?

a. glucagon
b. follicle stimulating hormone
c. leutinizing hormone
d. estrogen

answer d. estrogen

178 - comedk january 2008 paper mcqs with answers part 24

116q: which of the following drugs is most likely to cause myocardial depression ?

a. morphine
b. thiopental
c. etomidate
d. ketamine

answer b. thiopental

117q: congenital long QT syndrome is associated with neonatal ?

a. sinus bradycardia
b. sinus tachycardia
c. supra ventricular tachycardia
d. ventricular tachycardia

answer a. sinus bradycardia

118q: the interstitial lung disease ( ILD ) showing granulomas on lung biopsy is ?

a. usual interstitial pneumonitis
b. sarcoidosis
c. diffuse alveolar damage
d. desquamative interstitial pneumonia

answer b. sarcoidosis

119q: normal portal vein pressure is ?

a. less than 3 mm Hg
b. 3-5 mm Hg
c. 5-10 mm Hg
d. 10-12 mm Hg

answer c. 5-10 mm Hg

120q: the single most useful clinical sign of severity of pneumonia in a person without underlying lung disease is ?

a. temperature more than 38.5 degree Celsius
b. heart rate more than 100 / minute
c. systolic blood pressure less than 90 mm Hg
d. respiratory rate less than 30 / minute

answer d. respiratory rate less than 30/min

177 - comedk january 2008 paper mcqs with answers part 23

111q: vascular involvement and thromobosis is seen in ?

a. coccidioidomycosis
b. aspergillosis
c. mucormycosis
d. histoplasmosis

answer c. mucormycosis

112q: pawn ball megakaryocytes are characteristic of ?

a. myelodysplastic syndrome
b. idiopathic thrombocytopenic purpura
c. thrombotic thrombocytopenic purpura
d. chloramphenicol toxicity

answer a. myeloblastic syndrome

113q: argon laser trabeculoplasty is done in ?

a. open angle glaucoma
b. secondary glaucoma
c. angle recession glaucoma
d. angle closure glaucoma

answer a. open angle glaucoma

114q: the systolic ejection murmur in hypertrophic obstructive cardiomyopathy is diminished when a patient ?

a. performs the valsalva maneuver
b. lies down
c. inhales amyl nitrate
d. stands up

answer b. lies down

115q: multiple sites of narrowing of peripheral pulmonary artery occurs with ?

a. roseola
b. rubeola
c. rubella
d. rocio virus disease

answer c. rubella

176 - comedk january 2008 paper mcqs with answers part 22

106q: yellow fever is absent in India because ?

a. climatic conditions are not favourable
b. virus is not present
c. vector mosquito is absent
d. population is immune

answer b. virus is not present

107q: the objective of national population policy 2000 is to bring total fertility rate to replacement levels by the year ?

a. 2005
b. 2010
c. 2015
d. 2020

answer b. 2010

108q: mucin clot test is done to detect ?

a. mucin in stool
b. protein in CSF
c. hyaluronate in synovial fluid
d. protein in pleural fluid

answer c. hyaluronate in synovial fluid

109q: facial angle is a rough index of the degree of development of the ?

a. jaws
b. nose
c. brain
d. eyes

answer c. brain

110q: the epithelial lining of the urethra below the opening of the ejaculatory ducts is ?

a. stratified cuboidal epithelium
b. stratified columnar epithelium
c. transitional epithelium
d. stratified squamous epithelium

answer b. stratified columnar epithelium

175 - comedk january 2008 paper mcqs with answers part 21

101q: antipsychotic induced “akathisia” is characterized by ?

a. rigidity
b. tremor
c. spasm of muscle/ muscle group
d. restlessness

answer d. restlessness

102q: which one of the following causes of hypoxemia is not corrected by giving supplemental oxygen ?

a. ventilation perfusion mismatch
b. alveolar hypoventilation
c. impairment of diffusion
d. right to left shunt

answer d. right to left shunt

103q: moth eaten alopecia is seen in ?

a. black dot tinea
b. telogen effluvium
c. alopecia areata
d. secondary syphilis

answer d. secondary syphilis

104q: the most common benign tumor of the lung is ?

a. hamartoma
b. alveolar adenoma
c. teratoma
d. fibroma

answer a. hamartoma

105q: grey turner’s sign ( flank discoloration ) is seen in ?

a. acute pyelonephritis
b. acute cholecystitis
c. acute pancreatitis
d. acute peritonitis

answer c. acute pancreatitis

174 - comedk january 2008 paper mcqs with answers part 20

96q: refeeding edema is due to increased release of ?

a. growth hormone
b. glucocorticoids
c. insulin
d. thyroxine

answer c . insulin

97q: fetal erythropoesis first occurs at what week of gestation ?

a. 6
b. 10
c. 12
d. 14

answer a. 6 th week

98q: the most common site of ectopic phaeochromocytoma is ?

a. organ of zuckerkandl
b. bladder
c. filum terminale
d. celiac plexus

answer a. organ of zuckerkandl

99q: pitting of nails can be seen in ?

a. tinea unguium
b. alopecia areata
c. androgenetic alopecia
d. peripheral vascular disease

answer b. alopecia areata

100q: which of the following conditions is predominant in females ?

a. talipes equinovarus
b. cleft palate
c. congenital hip dislocation
d. pyloric stenosis

answer c. congenital hip dislocation

173 - comedk january 2008 paper mcqs with answers part 19

91q: which of the following antitumor agents works by impairing denovo purine synthesis ?

a. hydroxyl urea
b. 5- fluorouracil
c. Methotrexate
d. Allopurinol

answer c. methotrexate

92q: the dangerous particle size causing pneumoconiosis arises from ?

a. 100-150 micrometers
b. 50-100 micrometers
c. 10-50 micrometers
d. 1-5 micrometers

answer d. 1-5 micrometers

93q: swinging flash light test is used to examine ?

a. cornea
b. pupil
c. lens
d. conjunctiva

answer b. pupil

94q: the recommended content of iodine in salt at the consumer level is ?

a. 10 ppm
b. 15 ppm
c. 20 ppm
d. 30 ppm

answer b. 15 ppm

95q: which of the following does not cause an increase in serum amylase ?

a. pancreatitis
b. carcinoma lung
c. renal failure
d. cardiac failure

answer d. cardiac failure

172 - comedk january 2008 paper mcqs with answers part 18

86q: the ECG change seen in hyperkalemia is ?

a. narrowing of the QRS complex
b. increased amplitude of P waves
c. narrowing and peaking of T waves
d. prominent U waves

answer c. narrowing and peaking of T waves

87q: association of sexual precocity,multiple cystic bone lesions and endocrinopathies are seen in ?

a. McCune-Albright’s syndrome
b. Granulosa cell tumor
c. Androblastoma
d. Hepatoblastoma

answer a. McCune-Albright’s syndrome

88q: amaurosis fugax refers to occlusion of ?

a. middle cerebral artery
b. retinal artery
c. renal vessels
d. mesenteric vessels

answer b. retinal artery

89q: early and reliable indication of air embolism during anaesthesia can be obtained by continuous monitoring of ?

a. ECG
b. Blood pressure
c. End tidal CO2
d. Oxygen saturation

answer c. end tidal CO2

90q: the following is a life threatening side effect associated with the use of clozapine ?

a. pancreatitis
b. hypoglycemia
c. agranulocytosis
d. acute renal failure

answer c. agranulocytosis

171 - comedk january 2008 paper mcqs with answers part 17

81q: in the stomach H+ ions are secreted in exchange for ?

a. Na +
b. K +
c. Ca +
d. Cl –

answer b. K+

82q: the causative agent of favus is ?

a. microsporum audounii
b. microsporum canis
c. trichophyton mentagrophyte
d. trichophyton schoenleinii

answer d. trichophyton schoenleinii

83q: mycetoma is caused by the following agents except ?

a. allescheria boydii
b. madurella mycetomii
c. trichosporum beigelli
d. nocardia asteroids

answer c. trichosporum beigelli

84q: the poison that can be detected after death in hair is ?

a. lead
b. copper
c. mercury
d. arsenic

answer d. arsenic

85q: the following are grades of binocular single vision except ?

a. simultaneous macular perception
b. fusion
c. stereopsis
d. suppression

answer d. suppression

170 - comedk january 2008 paper mcqs with answers part 16

76q: copper sulphate poisoning manifests with ?

a. acute hemolysis
b. high anion gap acidosis
c. peripheral neuropathy
d. rhabdomyloysis

answer a. acute hemolysis

77q: a 28 year old complains of glare in both eyes . the cornea shows whorl like opacities of the epithelium. He also gave a history of long term treatment with amiodarone. The most likely diagnosis is ?

a. terrain’s marginal degeneration
b. cornea verticillata
c. band shaped keratopathy
d. arcus juvenalis

answer b. cornea verticillata

78q: the tumor causing polycythemia due to erythropoietin production is ?

a. cerebellar hemangioma
b. medulloblastoma
c. ependymoma
d. oligodendroglioma

answer a. cerebellar hemangioma

79q: in the mucosal cells , triglycerides are formed primarily in the ?

a. rough endoplasmic reticulum
b. smooth endoplasmic reticulum
c. golgi apparatus
d. ribosomes

answer b. smooth endoplasmic reticulum

80q: the last tributary of the azygous vein is ?

a. right superior intercostal vein
b. hemi-azygous vein
c. right bronchial vein
d. accessory azygous vein

answer c. right bronchial vein

169 - comedk january 2008 paper mcqs with answers part 15

71q: acute and recurrent pancreatitis is reported to occur in ?

a. homocystinuria
b. maple syrup urine disease
c. methyl malonic acidemia
d. tyrosinemia

answer c. methyl malonic acidemia

72q: long term use of lithium is associated with the following endocrine abnormality ?

a. hypothyroidism
b. diabetes mellitus
c. hyperthyroidism
d. cushing’s syndrome

answer a. hypothyroidism

73q: spina ventosa is caused by ?

a. tuberculosis
b. leprosy
c. brucellosis
d. sickle cell disease

answer a. tuberculosis

74q: the drug used in the treatment of idiopathic hypercalcuria is ?

a. allopurinol
b. frusemide
c. acetazolamide
d. thiazide

answer d. thiazide

75q: oral contraceptive pill of choice in a lactating woman is ?

a. monophasic pill
b. biphasic pill
c. triphasic pill
d. mini pill

answer d. mini pill

168 - comedk january 2008 paper mcqs with answers part 14

66q: Wilson’s disease is characterized by ?

a. low serum ceruloplasmin and low urinary copper
b. low serum ceruloplasmin and high urinary copper
c. high serum ceruloplasmin and low urinary copper
d. high serum ceruloplasmin and low urinary copper

answer b. low serum ceruloplasmin and high urinary copper

67q: partogram is used to ?

a. assess the fetal well-being in labour
b. assess the condition of the baby at birth
c. record the events of pregnancy
d. assess the progress of labour

answer d. assess the progress of labour

68q: the reynold’s pentad of fever,jaundice,right upper quadrant pain,septic shock and mental status change is typical of ?

a. cholangitis
b. hepatitis
c. cholecystitis
d. pancreatitis

answer a. cholangitis

69q: the drug that has the fastest onset of action in benign prostatic hyperplasia ?

a. finasteride
b. tamsulosin
c. dutasteride
d. flutamide

answer b. tamsulosin

70q: nipple shadows on chest radiographs characteristically have a sharp ?

a. lateral margin
b. medial margin
c. inferior margin
d. superior margin

answer a. lateral margin

167 - comedk january 2008 paper mcqs with answers part 13

61q: the raphe nuclei located in lower pons and medulla secrete the following neurotransmitter ?

a. norepinephrine
b. dopamine
c. serotonin
d. acetyl choline

answer c. serotonin

62q: superior colliculus is concerned with ?

a. olfaction
b. hearing
c. vision
d. pain sensation

answer c. vision

63q: berger nephropathy disease is due to mesangial deposition of ?

a. fibrin and C3
b. IgD and C3
c. IgE and C3
d. IgA and C3

answer d. Ig A and C3

64q: an emerging viral pathogen causing pyelonephritis in kidney allografts is ?

a. molluscum contagiosum
b. herpes simplex virus
c. polyoma virus
d. influenza virus

answer c. polyoma virus

65q: under the national programme for control of blindness , the goal is to reduce the prevalence the blindness to a level of ?

a. 0.1 %
b. 0.3 %
c. 0.5 %
d. 1 %

answer b. 0.3 %

166 - comedk january 2008 paper mcqs with answers part 12

56q: metrifonate is effective against ?

a. amoebiasis
b. leishmaniasis
c. schistosomiasis
d. giardiasis

answer c. schistosomiasis

57q: thrombocytopenia due to increased platelet destruction is seen in ?

a. aplastic anemia
b. cancer chemotherapy
c. acute leukemia
d. systemic lupus erythematosus

answer d. systemic lupus erythematosus

58q: case control study is a type of ?

a. descriptive epidemiological study
b. analytical study
c. longitudinal study
d. experimental epidemiological study

answer b. analytical study

59q: commonest complication of CSOM is ?

a. sub periosteal abscess
b. mastoiditis
c. brain abscess
d. meningitis

answer b. mastoiditis

60q: periodic acid Schiff stain shows block positivity in ?

a. myeloblasts
b. lymphoblasts
c. monoblasts
d. megakaryoblasts

answer b. lymphoblasts