24. Splicing activity seen in
a) mRNA
b) snRNA
c) tRNA
d) rRNA
25. After digestion by restriction endonucleases DNA strands can be joined again by
a) DNA polymerase
b) DNA ligase
c) DNA topoisomerase
d) DNA gyrase
26. Acetyl coA can be directly converted to all except
a) Glucose
b) Fatty acids
c) Cholesterol
d) Ketone bodies
27. After overnite fasing,levels of glucose tranporters reduced in
a) Brain
b) Muscle
c) Adipocytes
d) Hepatocyte
28. Insulin stimulates A/E
a) Glycolysis
b) Glycogenesis
c) Lipogenesis
d) Ketogenesis
29. Eukaryotic cell membrane contains A/E
a) Cholesterol
b) Triglycerides
c) Carbohydrates
d) Lecithin
30. All of the following are true bout sickle cell trait except
a) Single nucleotide change leads to a change from glutamate to valine
b) A single base pair change leads to RFLP
c) Deoxygenated Hb leads to the exposure of sticky end due to replacement of non polar residue by polar residue
d) Offers protection to malaria in heterozygotes
31. Hepatomegaly is the essential feature for all of the following except
a) Hepatic porphyria
b) Niemann Pick disease
c) Von Gierke’s disease
d) Hurler syndrome
32. A 40 yr old woman presents with progressive palmoplantar pigmentation. X-ray spine shows calcification of intervertebral discs. On adding Benedict’s reagent to urine, it gives
greenish brown precipitate and blue black supernatant fluid. What is the diagnosis?
a) Phenylketonuria
b) Alkaptonuria
c) Tyrosinemia type 2
d) Argininosuccinic aciduria
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