Thursday, June 19, 2008

33 - smoking cessation mcq - pgi june 2008 mcqs

Q.2 Drugs used for smoking cessation?


ans is a)Varenicline

Varenicline is a nicotinic receptor partial agonist. In this respect, it is similar to cytisine and different from nicotinic antagonist, bupropion, and nicotine replacement therapies (NRTs) like nicotine patches (commonly, "the patch") and nicotine gum. As a partial agonist, it both reduces cravings for and decreases the pleasurable effects of cigarettes and other tobacco products, and through these mechanisms, it can assist some patients in stopping smokingIndications
Varenicline is indicated for (suggested for use in) smoking cessation. It is an alternative to NRTs and agonist medication and has demonstrated greater efficacy than them in comparable studies.

Bupropion (INN; previously known as amfebutamone,Wellbutrin, Zyban) is an atypical antidepressant that acts as a norepinephrine and dopamine reuptake inhibitor, and nicotinic antagonist
Initially researched and marketed as an antidepressant, bupropion was subsequently found to be effective as a smoking cessation aid

for DNB JUNE 2008 MCQS click here

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