1q: antineutrophilic cytoplasmic ( ANCA ) antibodies are seen in all except ?
a. churg strauss syndrome
b. wegener's granulomatosis
c. microscopic polyangitis
d. polyarteritis nodosa
answer: d . polyarteritis nodosa .
antineutrophilic cytoplasmic antibodies are of two types
1. P - ANCA = perinuclear antineutrophilic cytoplasmic antibodies and
2. C - ANCA = antineutrophilic cytoplasmic antibodies directed against cytoplasmic proteinase-3
the causes of P - ANCA are
a. microscopic polyangitis ( microscopic PAN )
b. churg strauss syndrome
c. cresentric glomerulonephritis
d. good pasture syndrome
e. rarely seen in classic PAN
the causes of C - ANCA are
a. wegener's granulomatosis .