1q: side effects of timolol maleate ?
- asthma
- depression
- tachycardia
- hypotension
- hypertension
answer: a , b , d .
2q: methotrexate acts by ?
- inhibition of dihydrofolate reductase
- aldose dehydrogenase
- glutathione reductase
- inhibition of sterol synthesis
answer: a .
3q: true about carvedilol ?
- alpha 1 blocker
- beta 1 blocker
- beta 2 blocker
- antioxidant
- used in hypertension
answer: a , b , c , d , e .
4q: prophylaxis of migraine ?
- flunarizine
- cinarizine
- beta blockers
- sodium valproate
- carbamazepine
answer: a , c , d .
5q: which of the following are prodrugs ?
- mercaptopurine
- dipivefrine
- enalapril
- phenytoin
- linezolid
answer: a , b , c .
6q: first pass metabolism is seen in ?
- lignocaine
- propranolol
- salbutamol
- dypyridamol
- erythromycin
answer: a , b , c .
7q: true about quinidine
- it increases the effective refractory period
- used in hypertension
- causes paradoxical tachycardia
- it decreases absolute refractory period
- cinchonism is seen
answer: a , c , e .
8q: regarding ritonavir in AIDS patient which of the following are true ?
- interacts with terfenadine
- gastrointestinal symptoms are seen
- contraindicated in renal failure
- it is NNRTI
- should not be used in AIDS patient with bleeding disorder
answer: a , b .
9q: anti hypertensive drug beneficial or neutral role in lipid metabolism ?
- prazocin
- propranolol
- furosemide
- losartan
- chlorthiazide
answer: a , d . prazocin and losartan .
10q: neurochemical mechanism of analgesia
- VR-1
- Nicotinic cholinergic
- Nocistatin pattern
- Nociceptin pattern
- Anandomide
Answer: a, b , d , e .
11q: side effects of phenytoin are ?
- gum hypertrophy
- alopecia
- subungual exostosis
- onycholysis
- acne rosacea
answer: a .
12q: ototoxicity of aminoglycosides is increased with concurrent use of which of the following drugs ?
- cisplatin
- furosemide
- vancomycin
- vincristin
- erythromycin
answer: a , b , c , e .
13q: treatment of pencillinase producing neisseria gonorrhea is/are ?
- amoxicillin
- ciprofloxacin
- cefotaxime
- azithromycin
- doxycycline
answer: b , c .
14q: true about lispro-insulin ?
- action is faster and short in duration than regular insulin
- it is given 15 minutes prior to meal
- source is lamb
- action is faster and long in duration than regular insulin
answer: a , b .
15q: true about pseudocholine esterase ?
- present in neuromuscular junction
- level is increased in pregnancy
- succinyl choline is metabolized
- organophosphorous inhibits it
answer: c .
16q: alkylating agents are ?
- vincristin
- actinomycin-D
- chlorambucil
- 5-FU
- Cyclophosphamide
Answer: c , e .
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