Tuesday, March 8, 2011

418 - AP PG 2011 (Andhra pradesh) OBSTETRICS questions with answers

1q: The rate of production of which of the following hormone is highest during pregnancy?
a. HCG
b. HPL
c. Progesterone
d. Estradiol


There are five genes in the growth hormone–placental lactogen gene cluster that are linked and located on chromosome 17. Two of these genes, hPL2 and hPL3, both encode hPL, and the amount of mRNA in the term placenta is similar for each. In contrast, the prolactin gene is located on chromosome 6 (Owerbach and colleagues, 1980, 1981). The production rate of hPL near term, about 1 g/day, is the greatest, by far, of any known hormone in humans.

2q: Which of the following has the highest carbohydrate content?
a. HCG
b. HPL
c. Human pregnancy specific beta glycoprotein

Read the below lines taken from WILLIAMS OBSTETRICS 22ND EDITION :

Chorionic gonadotropin is a glycoprotein (molecular weight 36,000 to 40,000 d) with the highest carbohydrate (30 percent) content of any human hormone. The carbohydrate component, and especially the terminal sialic acid, protects the molecule from catabolism. The 36-hour plasma half-life of intact hCG is much longer than the 2 hours for LH. The hCG molecule is composed of two dissimilar subunits, designated (92 amino acids) and (145 amino acids), which are noncovalently linked. They are held together by electrostatic and hydrophobic forces that can be separated in vitro. Isolated subunits are unable to bind the LH receptor and thus lack biological activity.

3q: What happens to Central venous pressure during pregnancy?
a. Increases markedly
b. Increases slightly
c. Remains the same
d. Decreases

4q: Which type of placenta is called dangerous placenta
a. Type 2 anterior
b. Type 2 posterior
c. central

5q: The level of which of the following clotting factor is decreased in pregnancy?
a. 7
b. 9
c. 2
d. 11

1 comment:

shirisha said...

answer for 3q is central venous pressure is unchanged with pregnancy.

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